Journal of Clinical Densitometry
Volume 13, Issue 4 , Pages 462-466 , October 2010

Hypovitaminosis D and Bone Mineral Metabolism and Bone Density in Hyperthyroidism

  • Dinesh Kumar Dhanwal

      Affiliations

    • MRC Epidemiology Resource Centre, Southampton General Hospital, University of Southampton, Southampton, UK
    • Maulana Azad Medical College, New Delhi, India
    • Corresponding Author InformationAddress correspondence to: Dinesh K. Dhanwal, DM, Deapartment of Medicine (Endocrinology Division), Maulana Azad Medical College, New Delhi, India 110002.
    • ,
  • Narayana Kochupillai

      Affiliations

    • SRM Medical College, Kattankulathur, India
    • ,
  • Nandita Gupta

      Affiliations

    • All India Institute of Medical Sciences, New Delhi, India
    • ,
  • Cyrus Cooper

      Affiliations

    • MRC Epidemiology Resource Centre, Southampton General Hospital, University of Southampton, Southampton, UK
    • Botnar Research Centre, Institute of Musculoskeletal Sciences, University of Oxford, Oxford, UK
    • ,
  • Elaine M. Dennison

      Affiliations

    • MRC Epidemiology Resource Centre, Southampton General Hospital, University of Southampton, Southampton, UK

Received 14 April 2010 ,Revised 21 May 2010 ,Accepted 23 May 2010.

References 

  1. Inaba M. Secondary osteoporosis: thyrotoxicosis, rheumatoid arthritis, and diabetes mellitus. J Bone Miner Metab. 2004;22(4):287–292Review
  2. Mundy GR, Shapiro JL, Bandelin JG, et al. Direct stimulation of bone resorption by thyroid hormones. J Clin Invest. 1976;58:529–534
  3. Burman KD, Monchik JM, Earll JM, Wartofsky L. Ionized and total serum calcium and parathyroid hormone in hyperthyroidism. Ann Intern Med. 1976;84:668–671
  4. Goswami R, Tandon RK, Dndha A, Kochupillai N. Prevalence and significance of steatorrhea in patients with active Graves' disease. Am J Gastroenterol. 1998;93:1122–1125
  5. Goswami R, Kochupillai N. Adrenocortical reserve in patients with Graves' disease. Eur J Endocrinol. 2001;144:85
  6. Mithal A, Wahl DA, Bonjour JP, et al. IOF Committee of Scientific Advisors (CSA) Nutrition Working Group Global vitamin D status and determinants of hypovitaminosis D. Osteoporos Int. 2009;20:1807–1820
  7. Goswami R, Kochupillai N, Gupta N, et al. Presence of 25(OH) D deficiency in a rural North Indian village despite abundant sunshine. J Assoc Physicians India. 2008;56:755–757
  8. Goswami R, Shah P, Ammini AC. Thyrotoxicosis with osteomalacia and proximal myopathy. J Postgrad Med. 1993;39:89–90
  9. Nagasaka S, Shinobara Y, Kubota K, Murakamit . Osteomalacia in a vitamin D deficient women with Graves' disease. Endrocr J. 2001;48:515–516
  10. Udayakumar N, Chandrasekaran M, Rasheed MH, et al. Evaluation of bone mineral density in thyrotoxicosis. Singapore Med J. 2006;47:947–950
  11. Crooks J, Murray IP, Wayne EJ. Statistical methods applied to the clinical diagnosis of thyrotoxicosis. Q J Med. 1959;28(110):211–234
  12. McKenna MJ, Freanes R, Lasey OM, et al. Osteomalacia and osteoporosis: evaluation of a diagnostic index. J Clin Pathol. 1983;36:245–252
  13. Food composition tables. In:  Gopalan C,  Sastri BVR,  Balasubramanian SC editor. Nutritive value of Indian foods. Hyderabad, India: National Institute of Nutrition, Indian Council of Medical Research; 1996;p. 45–95
  14. Harinarayan CV, Gupta N, Kochupillai N. Vitamin D status in primary hyperparathyroidism. Clin Endocrinol (Oxf). 1995;43:351–358
  15. Goswami R, Gupta N, Goswami G, et al. Prevalence and significance of low 25 hydroxy vitamin D concentrations in healthy subjects in Delhi. Am J Clin Nutr. 2000;72:472–475
  16. Yamashita H, Nognchi S, Kakatsh K, et al. High prevalence of vitamin D deficiency in Japanese male patients with Graves'. Endocr J. 2001;48:63–69
  17. Doi Y, Yamashita H, Noguchi S. High prevalence of secondary hyperparathyroidism in Graves' disease. Clin Calcium. 2005;15(S1):68–70
  18. Mosekilde L, Lund B, Sorensen OH, et al. Serum 25-hydroxycholecalciferol in hyperthyroidism. Lancet. 1977;1:806
  19. Velentzas C, Orepoulos DB, From G, et al. Vitamin D levels in thyrotoxicosis. Lancet. 1977;1:370–371
  20. Szabo XS, Ritzl F. Hypercalcemia in hyperthyroidism—role of age and goiter type. Klin Wochenschr. 1981;59:275–279
  21. Parsons V, Anderson J. The maximum renal tubular reabsorptive rate for inorganic phosphate in thyrotoxicosis. Clin Sci. 1964;27:313–318
  22. Harden RM, Harrison MT, Alexander WD, Nordin BEC. Phosphate excretion and parathyroid function in thyrotoxicosis. J Endocrinol. 1964;28:281–288
  23. Mosekilde L, Eriksen EF, Charles P. Effects of thyroid hormones on bone and mineral metabolism. Endocrinol Metab Clin North Am. 1990;19:35–63
  24. van de Ven AC, Erdtsieck RJ. Changes of bone mineral density, quantitative ultrasound parameters and markers of bone turnover during treatment of hyperthyroidism. Neth J Med. 2008;66:428–432
  25. Jódar E, Muñoz-Torres M, Escobar-Jiménez F, et al. Bone loss in hyperthyroid patients and in former hyperthyroid patients controlled on medical therapy: influence of aetiology and menopause. Clin Endocrinol (Oxf). 1997;47:279–285

PII: S1094-6950(10)00196-4

doi: 10.1016/j.jocd.2010.05.008

Journal of Clinical Densitometry
Volume 13, Issue 4 , Pages 462-466 , October 2010

Article Tools