Journal of Clinical Densitometry
Volume 13, Issue 3 , Pages 267-276 , July 2010

Normative Bone Mineral Density Z-Scores for Canadians Aged 16 to 24 Years: The Canadian Multicenter Osteoporosis Study

  • Wei Zhou

      Affiliations

    • CaMos Methods Centre, McGill University, Montreal, Quebec, Canada
    • ,
  • Lisa Langsetmo

      Affiliations

    • CaMos Methods Centre, McGill University, Montreal, Quebec, Canada
    • ,
  • Claudie Berger

      Affiliations

    • CaMos Methods Centre, McGill University, Montreal, Quebec, Canada
    • ,
  • Jonathan D. Adachi

      Affiliations

    • Departments of Clinical Epidemiology and Biostatistics and Medicine, McMaster University, Hamilton, Ontario, Canada
    • ,
  • Alexandra Papaioannou

      Affiliations

    • Departments of Clinical Epidemiology and Biostatistics and Medicine, McMaster University, Hamilton, Ontario, Canada
    • ,
  • George Ioannidis

      Affiliations

    • Departments of Clinical Epidemiology and Biostatistics and Medicine, McMaster University, Hamilton, Ontario, Canada
    • ,
  • Colin Webber

      Affiliations

    • Departments of Clinical Epidemiology and Biostatistics and Medicine, McMaster University, Hamilton, Ontario, Canada
    • ,
  • Stephanie A. Atkinson

      Affiliations

    • Departments of Clinical Epidemiology and Biostatistics and Medicine, McMaster University, Hamilton, Ontario, Canada
    • ,
  • Wojciech P. Olszynski

      Affiliations

    • Department of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    • ,
  • Jacques P. Brown

      Affiliations

    • Department of Rheumatology and Immunology, Laval University, Quebec City, Quebec, Canada
    • ,
  • David A. Hanley

      Affiliations

    • Departments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    • ,
  • Robert Josse

      Affiliations

    • Departments of Medicine, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Nancy Kreiger

      Affiliations

    • CaMos National Coordinating Centre, McGill University, Montreal, Quebec, Canada
    • Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Jerilynn Prior

      Affiliations

    • Department of Medicine and Endocrinology, University of British Columbia, Vancouver, British Columbia, Canada
    • ,
  • Stephanie Kaiser

      Affiliations

    • Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    • ,
  • Susan Kirkland

      Affiliations

    • Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    • ,
  • David Goltzman

      Affiliations

    • CaMos National Coordinating Centre, McGill University, Montreal, Quebec, Canada
    • Department of Medicine, McGill University, Montreal, Quebec, Canada
    • ,
  • Kenneth Shawn Davison

      Affiliations

    • Corresponding Author InformationAddress correspondence to: Kenneth Shawn Davison, PhD, 2086 Byron St Victoria, BC V8R 1L9, Canada.
    • Department of Rheumatology and Immunology, Laval University, Quebec City, Quebec, Canada
    • ,
  • CaMos Research Group

      Affiliations

    • See Acknowledgments section for complete list of the members.

Received 6 October 2009 ,Revised 22 April 2010 ,Accepted 22 April 2010.

References 

  1. In:  Dent CE,  Frame B,  Parfitt AM,  Duncan H editor. Clinical aspects of metabolic bone disease. Amsterdam, The Netherlands: Excerpta Medica; 1973;p. 376–387
  2. Bachrach LK. Consensus and controversy regarding osteoporosis in the pediatric population. Endocr Pract. 2007;13:513–520
  3. Faulkner RA, Bailey DA. Osteoporosis: a pediatric concern?. Med Sport Sci. 2007;51:1–12
  4. Kanis JA. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: synopsis of a WHO report. WHO Study Group. Osteoporos Int. 1994;4:368–381
  5. Lewiecki EM, Gordon CM, Baim S, et al. International Society for Clinical Densitometry 2007 Adult and Pediatric Official Positions. Bone. 2008;43:1115–1121
  6. Gafni RI, Baron J. Overdiagnosis of osteoporosis in children due to misinterpretation of dual-energy x-ray absorptiometry (DEXA). J Pediatr. 2004;144:253–257
  7. Bailey DA, Martin AD, McKay HA, et al. Calcium accretion in girls and boys during puberty: a longitudinal analysis. J Bone Miner Res. 2000;15:2245–2250
  8. Sabatier JP, Guaydier-Souquieres G, Laroche D, et al. Bone mineral acquisition during adolescence and early adulthood: a study in 574 healthy females 10-24 years of age. Osteoporos Int. 1996;6:141–148
  9. Carey JJ, Delaney MF, Love TE, et al. DXA-generated Z-scores and T-scores may differ substantially and significantly in young adults. J Clin Densitom. 2007;10:351–358
  10. The Writing Group for the ISCD Position Development Conference. Diagnosis of osteoporosis in men, premenopausal women, and children [Position Statement]. J Clin Densitom. 2004;7:17–26
  11. Langsetmo L, Hanley DA, Kreiger N, et al. Geographic variation of bone mineral density and selected risk factors for prediction of incident fracture among Canadians 50 and older. Bone. 2008;43:672–678
  12. Kreiger N, Tenenhouse A, Joseph L, et al. Research note: the Canadian Multicentre Osteoporosis Study (CaMos)—background, rationale, methods. Can J Aging. 1999;18:376–387
  13. Ware JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992;30:473–483
  14. Looker AC, Wahner HW, Dunn WL, et al. Updated data on proximal femur bone mineral levels of US adults. Osteoporos Int. 1998;8:468–489
  15. Genant HK, Grampp S, Gluer CC, et al. Universal standardization for dual x-ray absorptiometry: patient and phantom cross-calibration results. J Bone Miner Res. 1994;9:1503–1514
  16. Hui SL, Gao S, Zhou XH, et al. Universal standardization of bone density measurements: a method with optimal properties for calibration among several instruments. J Bone Miner Res. 1997;12:1463–1470
  17. Lu Y, Fuerst T, Hui S, Genant HK. Standardization of bone mineral density at femoral neck, trochanter and Ward's triangle. Osteoporos Int. 2001;12:438–444
  18. Ozdemir AK, Ozdemir HD, Polat NT, et al. The effect of personality type on denture satisfaction. Int J Prosthodont. 2006;19:364–370
  19. Fan B, Lu Y, Genant H, et al. Does standardized BMD still remove differences between Hologic and GE-Lunar state-of-the-art DXA systems?. Osteoporos Int. 2009;[Epub ahead of print]
  20. Shapiro SS, Wilk MB. An analysis of variance test for normality (complete sample). Biometrika. 1965;52:591–611
  21. Tukey JW. Exploratory data analysis. Reading, MA: Addison-Wesley; 1977;
  22. Box GEP, Cox DR. An analysis of transformation. J R Stat Soc Ser B. 1964;26:211–252
  23. Joseph L, Reinhold C. Statistical inference for continuous variables. AJR Am J Roentgenol. 2005;184:1047–1056
  24. Raftery AE, Lewis SM. One long run with diagnostics: implementation strategies for Markov chain Monte Carlo. Stat Sci. 1992;7:493–497
  25. Bachrach LK, Hastie T, Wang MC, et al. Bone mineral acquisition in healthy Asian, Hispanic, black, and Caucasian youth: a longitudinal study. J Clin Endocrinol Metab. 1999;84:4702–4712
  26. In:  Higgins JPT,  Green S editor. Cochrane handbook for systematic reviews of interventions version 5.0.2. The Cochrane Collaboration; 2009;[updated September 2009]. Available online at www.cochrane-handbook.org
  27. Glass GV. Primary, secondary and meta-analysis of research. Educ Res. 1976;5:3–8
  28. Kroger H, Kotaniemi A, Vainio P, Alhava E. Bone densitometry of the spine and femur in children by dual-energy x-ray absorptiometry. Bone Miner. 1992;17:75–85
  29. Webber CE, Sala A, Barr RD. Accounting for body size deviations when reporting bone mineral density variables in children. Osteoporos Int. 2009;20:113–121
  30. Carter DR, Bouxsein ML, Marcus R. New approaches for interpreting projected bone densitometry data. J Bone Miner Res. 1992;7:137–145
  31. Nelson HD, Morris CD, Kraemer DF, et al. Osteoporosis in postmenopausal women: diagnosis and monitoring. Evid Rep Technol Assess (Summ) Feb;(28). 2001;1–2
  32. Papaioannou A, Kennedy CC, Cranney A, et al. Risk factors for low BMD in healthy men age 50 years or older: a systematic review. Osteoporos Int. 2009;20:507–518
  33. Israel E, Banerjee TR, Fitzmaurice GM, et al. Effects of inhaled glucocorticoids on bone density in premenopausal women. N Engl J Med. 2001;345:941–947
  34. Kemp JP, Osur S, Shrewsbury SB, et al. Potential effects of fluticasone propionate on bone mineral density in patients with asthma: a 2-year randomized, double-blind, placebo-controlled trial. Mayo Clin Proc. 2004;79:458–466
  35. Hanania NA, Chapman KR, Sturtridge WC, et al. Dose-related decrease in bone density among asthmatic patients treated with inhaled corticosteroids. J Allergy Clin Immunol. 1995;96:571–579
  36. Sivri A, Coplu L. Effect of the long-term use of inhaled corticosteroids on bone mineral density in asthmatic women. Respirology. 2001;6:131–134
  37. Fujita K, Kasayama S, Hashimoto J, et al. Inhaled corticosteroids reduce bone mineral density in early postmenopausal but not premenopausal asthmatic women. J Bone Miner Res. 2001;16:782–787
  38. Allen HD, Thong IG, Clifton-Bligh P, et al. Effects of high-dose inhaled corticosteroids on bone metabolism in prepubertal children with asthma. Pediatr Pulmonol. 2000;29:188–193
  39. Boot AM, de Jongste JC, Verberne AA, et al. Bone mineral density and bone metabolism of prepubertal children with asthma after long-term treatment with inhaled corticosteroids. Pediatr Pulmonol. 1997;24:379–384
  40. Egan JJ, Maden C, Kalra S, et al. A randomized, double-blind study comparing the effects of beclomethasone and fluticasone on bone density over two years. Eur Respir J. 1999;13:1267–1275
  41. Griffiths AL, Sim D, Strauss B, et al. Effect of high-dose fluticasone propionate on bone density and metabolism in children with asthma. Pediatr Pulmonol. 2004;37:116–121
  42. Luengo M, Picado C, Del Rio L, et al. Vertebral fractures in steroid dependent asthma and involutional osteoporosis: a comparative study. Thorax. 1991;46:803–806

PII: S1094-6950(10)00187-3

doi: 10.1016/j.jocd.2010.04.005

Journal of Clinical Densitometry
Volume 13, Issue 3 , Pages 267-276 , July 2010

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