The Changes of Bone Mineral Density in Relation to Body Mass Index and Aging Among Polish and Different Ethnic Women in the United States: Cross-sectional Studies

Wiacek, Magdalena; Skrzek, Anna; Ignasiak, Zofia; Zubrzycki, Igor Z.

doi:10.1016/j.jocd.2010.03.002

« Previous Next »Journal of Clinical Densitometry
Volume 13, Issue 3 , Pages 307-314, July 2010

The Changes of Bone Mineral Density in Relation to Body Mass Index and Aging Among Polish and Different Ethnic Women in the United States: Cross-sectional Studies

Magdalena Wiacek
- Current address: Laboratory of Developmental Biology, Department of Life Science, Hanyang University, Sungdong-gu Hangdang-dong 17, Seoul 133-791, Korea.
- Faculty of Physiotherapy, University School of Physical Education in Wroclaw, al. I.J. Paderewskiego 35, Wroclaw, Poland
Anna Skrzek
- The authors contributed equally to this work.
- Faculty of Physiotherapy, University School of Physical Education in Wroclaw, al. I.J. Paderewskiego 35, Wroclaw, Poland
Zofia Ignasiak
- The authors contributed equally to this work.
- Faculty of Physical Education, University School of Physical Education in Wroclaw, al. I.J. Paderewskiego 35, Wroclaw, Poland
Igor Z. Zubrzycki
- Address correspondence to: Igor Z. Zubrzycki, PhD, Department of Life Science, Hanyang University, Sungdong-gu Hangdang-dong 17, Seoul 133-791, Korea.
- Department of Life Science, Hanyang University, Sungdong-gu Hangdang-dong 17, Seoul, Korea

Received 6 December 2009; received in revised form 4 March 2010; accepted 4 March 2010. published online 31 May 2010.

Abstract

In the present study, we analyzed the changes of bone mineral density (BMD) among Polish women age 40–79, as a function of biological aging and body mass index (BMI) class, and compared them with the US sample (National Health and Nutrition Examination Survey III). The null hypothesis of this study was that the rate of BMD change is femoral region, age, ethnicity, and BMI dependent. The studied group was divided into 4 age decades: 40–49, 50–59, 60–69, and 70–79 and 2 BMI classes (normal: 18.5≤BMI≤24.99 and obese: BMI>24.99). Analysis of covariance technique, using a generalized linear model with age and BMI as covariates, was used for data analysis. The influence of weight, height, and BMI on BMD loss was analyzed using multivariate regression analysis. The changes in BMD of femoral neck and trochanter are congruent. BMD decrease is not only age dependent but also, for specific ethnic groups, weight, height, and BMI dependent. The obtained results indicate that the analysis of age-dependent BMD changes should be performed by means of regression analysis using a broad age range rather than an age-decade approach.