Journal of Clinical Densitometry
Volume 13, Issue 2 , Pages 151-160 , April 2010

Assessing Body Composition in Healthy Newborn Infants: Reliability of Dual-Energy X-Ray Absorptiometry

  • Kristin Godang

      Affiliations

    • Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
    • Corresponding Author InformationAddress correspondence to: Kristin Godang, BSc.E., Section of Endocrinology, Oslo University Hospital, Rikshospitalet, N-0027 Oslo, Norway.
  • ,
  • Elisabeth Qvigstad

      Affiliations

    • Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
  • ,
  • Nanna Voldner

      Affiliations

    • Department of Obstetrics and Gynecology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
  • ,
  • Gunhild A. Isaksen

      Affiliations

    • Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
  • ,
  • Kathrine F. Frøslie

      Affiliations

    • Department of Obstetrics and Gynecology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
    • National Resource Centre for Women's Health, Oslo University Hospital, Rikshospitalet, Oslo, Norway
    • Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
  • ,
  • Jacob Nøtthellen

      Affiliations

    • Department of Medical Physics, Oslo University Hospital, Rikshospitalet, Oslo, Norway
  • ,
  • Tore Henriksen

      Affiliations

    • Department of Obstetrics and Gynecology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
  • ,
  • Jens Bollerslev

      Affiliations

    • Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway

Received 17 September 2009 ,Revised 18 January 2010 ,Accepted 18 January 2010.

References 

  1. Kim J, Wang Z, Heymsfield SB, et al. Total-body skeletal muscle mass: estimation by a new dual-energy X-ray absorptiometry method. Am J Clin Nutr. 2002;76(2):378–383
  2. Visser M, Pahor M, Tylavsky F, et al. One- and two-year change in body composition as measured by DXA in a population-based cohort of older men and women. J Appl Physiol. 2003;94(6):2368–2374
  3. Zamboni M, Zoico E, Scartezzini T, et al. Body composition changes in stable-weight elderly subjects: the effect of sex. Aging Clin Exp Res. 2003;15(4):321–327
  4. Kalender WA. Effective dose values in bone mineral measurements by photon absorptiometry and computed tomography. Osteoporos Int. 1992;2(2):82–87
  5. Laskey MA, Flaxman ME, Barber RW, et al. Comparative performance in vitro and in vivo of Lunar DPX and Hologic QDR-1000 dual energy X-ray absorptiometers. Br J Radiol. 1991;64(767):1023–1029
  6. Lewis MK, Blake GM, Fogelman I. Patient dose in dual x-ray absorptiometry. Osteoporos Int. 1994;4(1):11–15
  7. Lukaski HC. Soft tissue composition and bone mineral status: evaluation by dual-energy X-ray absorptiometry. J Nutr. 1993;123(2 Suppl):438–443
  8. Wahner HW, Dunn WL, Brown ML, et al. Comparison of dual-energy x-ray absorptiometry and dual photon absorptiometry for bone mineral measurements of the lumbar spine. Mayo Clin Proc. 1988;63(11):1075–1084
  9. Wahner HW, Looker A, Dunn WL, et al. Quality control of bone densitometry in a national health survey (NHANES III) using three mobile examination centers. J Bone Miner Res. 1994;9(6):951–960
  10. Kelly TL, Slovik DM, Schoenfeld DA, Neer RM. Quantitative digital radiography versus dual photon absorptiometry of the lumbar spine. J Clin Endocrinol Metab. 1988;67(4):839–844
  11. Kaymakci B, Wark JD. Precise accurate mineral measurements of excised sheep bones using X-ray densitometry. Bone Miner. 1994;25(3):231–246
  12. Swennen Q, Janssens GP, Geers R, et al. Validation of dual-energy x-ray absorptiometry for determining in vivo body composition of chickens. Poult Sci. 2004;83(8):1348–1357
  13. Muscaritoli M, Gleason JR, Meguid MM, Lukaski HC. Densitometry-based equations for estimating body composition in Fischer rats. Nutrition. 1993;9(5):439–445
  14. Rikans LE, Venkataraman PS, Cai Y. Evaluation by dual-energy X-ray absorptiometry of age-related changes in body composition of male rats. Mech Ageing Dev. 1993;71(1–2):155–158
  15. Chan GM. Performance of dual-energy x-ray absorptiometry in evaluating bone, lean body mass, and fat in pediatric subjects. J Bone Miner Res. 1992;7(4):369–374
  16. Venkataraman PS, Ahluwalia BW. Total bone mineral content and body composition by x-ray densitometry in newborns. Pediatrics. 1992;90(5):767–770
  17. Brunton JA, Weiler HA, Atkinson SA. Improvement in the accuracy of dual energy x-ray absorptiometry for whole body and regional analysis of body composition: validation using piglets and methodologic considerations in infants. Pediatr Res. 1997;41(4 Pt 1):590–596
  18. Ellis KJ, Shypailo RJ, Pratt JA, Pond WG. Accuracy of DXA-based body composition measurements for pediatric studies. Basic Life Sci. 1993;60:153–156
  19. Koo WW, Massom LR, Walters J. Validation of accuracy and precision of dual energy X-ray absorptiometry for infants. J Bone Miner Res. 1995;10(7):1111–1115
  20. Brunton JA, Bayley HS, Atkinson SA. Body composition analysis by dual energy X-ray absorptiometry compared to chemical analysis of fat, lean and bone mass in small piglets. Basic Life Sci. 1993;60:157–160
  21. Laskey MA. Dual-energy X-ray absorptiometry and body composition. Nutrition. 1996;12(1):45–51
  22. Mazess RB, Barden HS, Bisek JP, Hanson J. Dual-energy x-ray absorptiometry for total-body and regional bone-mineral and soft-tissue composition. Am J Clin Nutr. 1990;51(6):1106–1112
  23. Rigo J, Nyamugabo K, Picaud JC, et al. Reference values of body composition obtained by dual energy X-ray absorptiometry in preterm and term neonates. J Pediatr Gastroenterol Nutr. 1998;27(2):184–190
  24. Voldner N, Froslie KF, Bo K, et al. Modifiable determinants of fetal macrosomia: role of lifestyle-related factors. Acta Obstet Gynecol Scand. 2008;87(4):423–429
  25. Branson RS, Vaucher YE, Harrison GG, et al. Inter- and intra-observer reliability of skinfold thickness measurements in newborn infants. Hum Biol. 1982;54(1):137–143
  26. Dauncey MJ, Gandy G, Gairdner D. Assessment of total body fat in infancy from skinfold thickness measurements. Arch Dis Child. 1977;52(3):223–227
  27. Georgieff MK, Sasanow SR, Mammel MC, Pereira GR. Mid-arm circumference/head circumference ratios for identification of symptomatic LGA, AGA, and SGA newborn infants. J Pediatr. 1986;109(2):316–321
  28. Johnson TS, Engstrom JL. State of the science in measurement of infant size at birth. Newborn Infant Nurs Rev. 2002;2(3):150–158
  29. Koo WW, Walters J, Bush AJ. Technical considerations of dual-energy X-ray absorptiometry-based bone mineral measurements for pediatric studies. J Bone Miner Res. 1995;10(12):1998–2004
  30. Normalised organ doses for paediatric X-Ray examinations calculated using Monte Carlo techniques. National Radiation Protection Board, England. NRPB-SR279, 1996.
  31. Lunar Corporation, Madison, Wisconsin: Prodigy Safety and Specification. 2005.
  32. Gately PJ, Radley D, Cooke CB, et al. Comparison of body composition methods in overweight and obese children. J Appl Physiol. 2003;95(5):2039–2046
  33. Nord RH, Crenshaw TD, Schneider DK, et al. Body composition measurements on small animals with the GE Lunar Prodigy. Presented at the July 2002 International Bone Densitometry Workshop, Monterey, CA. Presentation number: SU 100 2002.
  34. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;1(8476):307–310
  35. Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977;33(1):159–174
  36. International Society for Clinical Densitometry (ISCD) . Available at www.iscd.orgAccessed: February 4, 2009
  37. Schmelzle HR, Fusch C. Body fat in neonates and young infants: validation of skinfold thickness versus dual-energy X-ray absorptiometry. Am J Clin Nutr. 2002;76(5):1096–1100
  38. Slaughter MH, Lohman TG, Boileau RA, et al. Skinfold equations for estimation of body fatness in children and youth. Hum Biol. 1988;60(5):709–723
  39. Braillon PM, Berard J, Chatelain P, Pracros JP. [Dual energy x-ray absorptiometry assessment of the bone mineral content and body composition during growth], J Radiol. 2002;83(5):627–633
  40. Shypailo RJ, Ellis KJ. Bone assessment in children: comparison of fan-beam DXA analysis. J Clin Densitom. 2005;8(4):445–453
  41. Shypailo RJ, Butte NF, Ellis KJ. DXA: can it be used as a criterion reference for body fat measurements in children?. Obesity (Silver Spring). 2008;16(2):457–462
  42. Plank LD. Dual-energy X-ray absorptiometry and body composition. Curr Opin Clin Nutr Metab Care. 2005;8(3):305–309
  43. Elowsson P, Forslund AH, Mallmin H, et al. An evaluation of dual-energy X-Ray absorptiometry and underwater weighing to estimate body composition by means of carcass analysis in piglets. J Nutr. 1998;128(9):1543–1549
  44. Testolin CG, Gore R, Rivkin T, et al. Dual-energy X-ray absorptiometry: analysis of pediatric fat estimate errors due to tissue hydration effects. J Appl Physiol. 2000;89(6):2365–2372
  45. Hammami M, Koo WW, Hockman EM. Technical considerations for fan-beam dual-energy x-ray absorptiometry body composition measurements in pediatric studies. JPEN J Parenter Enteral Nutr. 2004;28(5):328–333
  46. Madsen OR, Jensen JE, Sorensen OH. Validation of a dual energy X-ray absorptiometer: measurement of bone mass and soft tissue composition. Eur J Appl Physiol Occup Physiol. 1997;75(6):554–558
  47. Ulijaszek SJ, Kerr DA. Anthropometric measurement error and the assessment of nutritional status. Br J Nutr. 1999;82(3):165–177
  48. Bhatia P, Johnson KJ, Bell EF. Variability of abdominal circumference of premature infants. J Pediatr Surg. 1990;25(5):543–544
  49. Johnson TS, Engstrom JL, Gelhar DK. Intra- and interexaminer reliability of anthropometric measurements of term infants. J Pediatr Gastroenterol Nutr. 1997;24(5):497–505
  50. Kispert CP, Merrifield HH. Interrater reliability of skinfold fat measurements. Phys Ther. 1987;67(6):917–920
  51. Baim S, Wilson CR, Lewiecki EM, et al. Precision assessment and radiation safety for dual-energy X-ray absorptiometry: position paper of the International Society for Clinical Densitometry. J Clin Densitom. 2005;8(4):371–378
  52. Sheng HP, Muthappa PB, Wong WW, Schanler RJ. Pitfalls of body fat assessments in premature infants by anthropometry. Biol Neonate. 1993;64(5):279–286
  53. Fogelholm M, van Marken LW. Comparison of body composition methods: a literature analysis. Eur J Clin Nutr. 1997;51(8):495–503

 Disclosures: The authors have individually nothing to declare for this study.

PII: S1094-6950(10)00122-8

doi: 10.1016/j.jocd.2010.01.121

Journal of Clinical Densitometry
Volume 13, Issue 2 , Pages 151-160 , April 2010