Journal of Clinical Densitometry
Volume 12, Issue 2 , Pages 200-206 , April 2009

Contribution of Fat-Free Mass and Fat Mass to Bone Mineral Density Among Reproductive-Aged Women of White, Black, and Hispanic Race/Ethnicity

Received 15 August 2008 ,Revised 12 January 2009 ,Accepted 13 January 2009.

References 

  1. Khosla S, Atkinson EJ, Riggs BL, et al. Relationship between body composition and bone mass in women. J Bone Miner Res. 1996;11:857–863
  2. Witzke KA, Snow CM. Lean body mass and leg power best predict bone mineral density in adolescent girls. Med Sci Sports Exerc. 1999;31:1558–1563
  3. Wang MC, Bachrach LK, Van Loan M, et al. The relative contributions of lean tissue mass and fat mass to bone density in young women. Bone. 2005;37:474–481
  4. Bakker I, Twisk JW, Van Mechelen W, et al. Fat-free body mass is the most important body composition determinant of 10-yr longitudinal development of lumbar bone in adult men and women. J Clin Endocrinol Metab. 2003;88:2607–2613
  5. Sowers MF, Kshirsagar A, Crutchfield MM, et al. Joint influence of fat and lean body composition compartments on femoral bone mineral density in premenopausal women. Am J Epidemiol. 1992;136:257–265
  6. Blum M, Harris SS, Must A, et al. Leptin, body composition and bone mineral density in premenopausal women. Calcif Tissue Int. 2003;73:27–32
  7. Lindsay R, Cosman F, Herrington BS, et al. Bone mass and body composition in normal women. J Bone Miner Res. 1992;7:55–63
  8. Reid IR, Plank LD, Evans MC. Fat mass is an important determinant of whole body bone density in premenopausal women but not in men. J Clin Endocrinol Metab. 1992;75:779–782
  9. Reid IR, Legge M, Stapleton JP, et al. Regular exercise dissociates fat mass and bone density in premenopausal women. J Clin Endocrinol Metab. 1995;80:1764–1768
  10. Winters KM, Snow CM. Body composition predicts bone mineral density and balance in premenopausal women. J Womens Health Gend Based Med. 2000;9:865–872
  11. Liu JM, Zhao HY, Ning G, et al. Relationship between body composition and bone mineral density in healthy young and premenopausal Chinese women. Osteoporos Int. 2004;15:238–242
  12. Douchi T, Yamamoto S, Oki T, et al. Difference in the effect of adiposity on bone density between pre- and postmenopausal women. Maturitas. 2000;34:261–266
  13. Lazcano-Ponce E, Tamayo J, Cruz-Valdez A, et al. Peak bone mineral area density and determinants among females aged 9 to 24 years in Mexico. Osteoporos Int. 2003;14:539–547
  14. Berenson AB, Odom SD, Radecki Breitkopf C, et al. Physiologic and psychologic symptoms associated with use of injectable contraception and 20 microgram oral contraceptive pills. Am J Obstet Gynecol. 2008;199:351.e1–12
  15. Marshall D, Johnell O, Wedel H. Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ. 1996;312:1254–1259
  16. Carter DR, Bouxsein ML, Marcus R. New approaches for interpreting projected bone densitometry data. J Bone Miner Res. 1992;7:137–145
  17. Katzman DK, Bachrach LK, Carter DR, et al. Clinical and anthropometric correlates of bone mineral acquisition in healthy adolescent girls. J Clin Endocrinol Metab. 1991;73:1332–1339
  18. Baim S, Wilson CR, Lewiecki EM, et al. Precision assessment and radiation safety for dual-energy X-ray absorptiometry: position paper of the International Society for Clinical Densitometry. J Clin Densitom. 2005;8:371–378
  19. Ravaud P, Reny JL, Giraudeau B, et al. Individual smallest detectable difference in bone mineral density measurements. J Bone Miner Res. 1999;14:1449–1456
  20. Kerr DA, Papalia S, Morton A, et al. Bone mass in young women is dependent on lean body mass. J Clin Densitom. 2007;10:319–326
  21. Schoenau E, Neu CM, Beck B, et al. Bone mineral content per muscle cross-sectional area as an index of the functional muscle-bone unit. J Bone Miner Res. 2002;17:1095–1101
  22. Tudor-Locke C, McColl RS. Factors related to variation in premenopausal bone mineral status: a health promotion approach. Osteoporos Int. 2000;11:1–24
  23. Ilich-Ernst J, Brownbill RA, Ludemann MA, Fu R. Critical factors for bone health in women across the age span: how important is muscle mass?. Medscape Womens Health. 2002;7:2
  24. Frost HM. Muscle, bone, and the Utah paradigm: a 1999 overview. Med Sci Sports Exerc. 2000;32:911–917
  25. Ferretti JL, Capozza RF, Cointry GR, et al. Gender-related differences in the relationship between densitometric values of whole-body bone mineral content and lean body mass in humans between 2 and 87 years of age. Bone. 1998;22:683–690
  26. Rittweger J, Beller G, Ehrig J, et al. Bone-muscle strength indices for the human lower leg. Bone. 2000;27:319–326
  27. Barbeau P, Gutin B, Litaker M, et al. Correlates of individual differences in body-composition changes resulting from physical training in obese children. Am J Clin Nutr. 1999;69:705–711
  28. Kyle UG, Morabia A, Schutz Y, Pichard C. Sedentarism affects body fat mass index and fat-free mass index in adults aged 18 to 98 years. Nutrition. 2004;20:255–260
  29. Kalkwarf HJ, Zemel BS, Gilsanz V, et al. The bone mineral density in childhood study: bone mineral content and density according to age, sex, and race. J Clin Endocrinol Metab. 2007;92:2087–2099
  30. Ettinger B, Sidney S, Cummings SR, et al. Racial differences in bone density between young adult black and white subjects persist after adjustment for anthropometric, lifestyle, and biochemical differences. J Clin Endocrinol Metab. 1997;82:429–434
  31. Young D, Hopper JL, Macinnis RJ, et al. Changes in body composition as determinants of longitudinal changes in bone mineral measures in 8 to 26-year-old female twins. Osteoporos Int. 2001;12:506–515

 All authors declare that they have no conflicts of interest or disclosures.

PII: S1094-6950(09)00004-3

doi: 10.1016/j.jocd.2009.01.002

Journal of Clinical Densitometry
Volume 12, Issue 2 , Pages 200-206 , April 2009