Journal of Clinical Densitometry
Volume 10, Issue 1 , Pages 76-85 , January 2007

Skeletal and Muscular Status in Juveniles With GFD Treated Clinical and Newly Diagnosed Atypical Celiac Disease—Preliminary Data

  • Paweł Płudowski

      Affiliations

    • Departments of Biochemistry and Experimental Medicine, The Children's Memorial Health Institute, Warsaw, Poland
    • ,
  • Elżbieta Karczmarewicz

      Affiliations

    • Departments of Biochemistry and Experimental Medicine, The Children's Memorial Health Institute, Warsaw, Poland
    • ,
  • Jerzy Socha

      Affiliations

    • Gastroenterology, Hepatology and Immunology, The Children's Memorial Health Institute, Warsaw, Poland
    • ,
  • Halina Matusik

      Affiliations

    • Departments of Biochemistry and Experimental Medicine, The Children's Memorial Health Institute, Warsaw, Poland
    • ,
  • Małgorzata Syczewska

      Affiliations

    • Pediatric Rehabilitation, The Children's Memorial Health Institute, Warsaw, Poland
    • ,
  • Roman S. Lorenc

      Affiliations

    • Departments of Biochemistry and Experimental Medicine, The Children's Memorial Health Institute, Warsaw, Poland
    • Corresponding Author InformationAddress correspondence to: Prof. Roman S. Lorenc, MD, PhD, Department of Biochemistry and Experimental Medicine, The Children's Memorial Health Institute, Aleja Dzieci Polskich 20, 04-736, Warsaw, Poland.

Received 1 September 2006 ,Revised 26 October 2006 ,Accepted 26 October 2006.

References 

  1. Farrell R, Kelly C. Diagnosis of celiac sprue. Am J Gastroenterol. 2001;96:3237–3246
  2. Farrell R, Kelly C. Celiac sprue. N Engl J Med. 2002;346:180–188
  3. Mäki M, Collin P. Coeliac disease. Lancet. 1997;349:1755–1759
  4. Branski D, Troncone R. Coeliac disease: a reappraisal. J Pediatr. 1988;133:181–187
  5. Cerf-Bensussan N, Cellier C, Heyman M, et al. Coeliac disease: an update on facts and questions based on the 10th international symposium on coeliac disease. J Pediatr Gastroenterol Nutr. 2003;37:412–421
  6. Cranney A, Rostom A, Sy R, et al. Consequences of testing for celiac disease. Gastroenterology. 2005;128:109–120
  7. Bai JC, Gonzalez D, Mautalen C, et al. Long-term effect of gluten restriction on bone mineral density of patients with coeliac disease. Aliment Pharmacol Ther. 1997;11:157–164
  8. Sategna-Guidetti C, Grosso SB, Grosso S, et al. The effects of 1-year gluten withdrawal on bone mass, bone metabolism and nutritional status in newly-diagnosed adult coeliac disease patients. Aliment Pharmacol Ther. 2000;14:35–43
  9. Valdimarsson T, Lofman O, Toss G, Strom M. Reversal of osteopenia with diet in adult coeliac disease. Gut. 1996;38:322–327
  10. Vasquez H, Mazure R, Gonzalez D, et al. Risk of fractures in celiac disease patients: a cross-sectional, case-control study. Am J Gastroenterol. 2000;95:183–189
  11. Vestergaard P, Mosekilde L. Fracture risk in patients with celiac disease, Crohn's disease, and ulcerative colitis: a nationwide follow-up study of 16416 patients in Denmark. Am J Epidemiol. 2002;156:10
  12. Thomason K, West J, Logan RFA, Coupland C, Holmes GKT. Fracture experience of patients with coeliac disease: a population based survey. Gut. 2003;52:518–522
  13. Gilsanz V. Bone density in children: a review of the available techniques and indications. Eur J Radiol. 1998;26:1771–1782
  14. Leonard MB, Propert KJ, Zemel BS, Stallings VA, Feldman HI. Discrepancies in pediatric bone mineral density reference data: potential for misdiagnosis of osteopenia. J Pediatr. 1998;135:182–188
  15. Prentice A, Parsons TJ, Cole TJ. Uncritical use of bone mineral density in absorptiometry may lead to size-related artifacts in the identification of bone mineral determinants. Am J Clin Nutr. 1994;60:837–842
  16. Molgaard C, Thomsen BL, Prentice A, Cole TJ, Michaelsen KF. Whole body bone mineral content in healthy children and adolescents. Arch Dis Child. 1997;76:9–15
  17. Katzman DK, Bachrach LK, Carter DR, Marcus R. Clinical and anthropometric correlates of bone mineral acquisition in healthy adolescent girls. J Clin Endocrinol Metab. 1991;73:1332–1339
  18. De Luca F, Baron J. Skeletal maturation. Endocrinologist. 1999;9:286–292
  19. Tothill P, Hannan WJ. Bone mineral and soft tissue measurements by dual-energy x-ray absorptiometry during growth. Bone. 2002;31:492–496
  20. Ferreti JL, Capozza RF, Cointry GR. Gender related differences in the relationship between densitometric values of whole-body bone mineral content and lean body mass in humans. Bone. 1998;22:683–690
  21. Högler W, Briody J, Woodhead . Importance of lean mass in the interpretation of total body densitometry in children and adolescents. J Pediatr. 2003;143:81–88
  22. Crabtree NJ, Kibirige MS, Fordham JN, et al. The relationship between lean body mass and bone mineral content in paediatric health and disease. Bone. 2004;35:965–972
  23. Płudowski P, Matusik H, Olszaniecka M, Lebiedowski M, Lorenc RS. Reference values for the indicators of skeletal and muscular status of healthy polish children. J Clin Densitom. 2005;82:164–177
  24. Petit MA, Beck TJ, Kontulainen SA. Examining the developing bone: what do we measure and how do we do it?. J Musculoskelet Neuronal Interact. 2005;5(3):213–224
  25. Rujner J, Socha J, Syczewska M, Wojtasik A, Kunachowicz H, Stolarczyk A. Magnesium status in children and adolescents with coeliac disease without malabsorption symptoms. Clin Nutr. 2004;23:1074–1079
  26. Walker-Smith JA, Guandalini S, Schmitz J, Schmerling DH, Visakorpi JK. Revised criteria for the diagnosis of coeliac disease. Arch Dis Child. 1990;65:909–911
  27. Rujner J, Socha J, Barra E. Serum and salivary antigliadin antibodies and serum IgA anti-endomysium antibodies as a screening test for coeliac disease. Acta Pediatr. 1996;85:814–817
  28. International Society for Clinical Densitometry . Official positions. Available at: www.iscd.org2006;
  29. Mora S, Barera G. Bone mass and bone metabolism in pediatric gastrointestinal disorders. J Pediatr Gastroenterol Nutr. 2004;39:129–140
  30. Ciacci C, Maurelli L, Klain M, Sabbatini F, Salvatore M, Mazzacca G. Calcium homeostasis and adult celiac disease: age related recovery of bone mineral density after gluten-free diet. Gut. 1994;35:197
  31. Szathmari M, Tulassay T, Arato A, Bodanszky H, Szabo A, Tulussay Z. Bone mineral content and density in asymptomatic children with coeliac disease on a gluten-free diet. Eur J Gastroenterol Hepatol. 2001;13:419–424
  32. Barera G, Mora S, Brambilla P, et al. Body composition in children with celiac disease and the effects of a gluten-free diet: prospective case-control study. Am J Clin Nutr. 2000;72:71–75
  33. Frost HM. Structural adaptations to mechanical usage (SATMU): 1. Redefining Wolff's law: the bone modeling problem. Anat Rec. 1990;226:403–413
  34. Frost HM. On defining osteopenias and osteoporoses: problems! Another view (with insights from a new paradigm). Bone. 1997;20:385
  35. Frost HM, Schoenau E. “The muscle-bone unit” in children and adolescents. J Pediatr Endocrinol Metab. 2000;13:571
  36. Schönau E, Neu CM, Beck B, Manz F, Rauch F. Bone mineral content per muscle cross-sectional area as an index of the functional muscle-bone unit. J Bone Miner Res. 2002;6:1095–1101
  37. Schönau E. The development of the skeletal system in children and the influence of muscular strength. Horm Res. 1996;49:27–31
  38. Schönau E, Werhahn E, Schiedermaier U, et al. Influence of muscle strength on bone strength during childhood and adolescence. Horm Res. 1996;45(Suppl 1):63–66
  39. Płudowski P, Lebiedowski M, Olszaniecka M, Marowska J, Matusik H, Lorenc RS. Idiopathic juvenile osteoporosis—an analysis of muscle-bone relationship. Osteoporos Int. 2006;17:1681–1690
  40. Bass SL, Eser P, Daly R. The effect of exercise and nutrition on the mechanostat. J Musculoskelet Neuronal Interact. 2005;5(3):239–254
  41. Schiessl H, Frost HM, Jee WSS. Estrogen and bone-muscle strength and mass relationships. Bone. 1998;22:1–6
  42. Jarvinen TLN, Kannus P, Sievanen H. Estrogen and bone—a reproductive and locomotive perspective. J Bone Miner Res. 2003;18:1921–1931

PII: S1094-6950(06)00304-0

doi: 10.1016/j.jocd.2006.10.005

Journal of Clinical Densitometry
Volume 10, Issue 1 , Pages 76-85 , January 2007

Article Tools

* Image Usage & Resolution