Journal of Clinical Densitometry
Volume 9, Issue 4 , Pages 419-424 , October 2006

Differences of Vertebral Area in Serial Bone Density Measurements: A Common Source of Potential Error in Interpretation of BMD Change

Received 13 July 2006 ,Revised 4 August 2006 ,Accepted 14 August 2006.

References 

  1. Liberman UR, Weiss SR, Broll J, et al. Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. N Engl J Med. 1995;333:1437–1443
  2. Harris ST, Watts NB, Genant HK, et al. Effects of risedronate treatment on vertebral and non-vertebral fractures in women with postmenopausal osteoporosis. JAMA. 1999;282:1344–1352
  3. Ettinger B, Black DM, Mitlak BH, et al. Reduction of vertebral fracture risk in post menopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. JAMA. 1999;282:637–645
  4. Cranney A, Guyatt G, Griffith L, et al. Osteoporosis Methodology Group and The Osteoporosis Research Advisory Group. Meta-analysis of therapies for postmenopausal osteoporosis IX. Summary of meta-analysis of therapies for postmenopausal osteoporosis. Endocr Rev. 2002;23:570–578
  5. Hochberg MC, Greenspan S, Wasnich RD, et al. Changes in bone density and turnover explain the reductions in incidence of nonvertebral fractures that occur during treatment with antiresorptive agents. J Clin Endocrinol Metab. 2002;12:281–289
  6. Bonnick SL. “Bone Densitometry in Clinical Practice: Application and Interpretation.”. New Jersey: Humana Press; 2004;
  7. Girardi FP, Parvataneni HK, Sandhu HS, et al. Correlation between vertebral body rotation and two-dimensional vertebral bone density measurement. Osteoporos Int. 2001;12:738–740
  8. Phillipov G, Seaborn CJ, Phillips PJ. Reproducibility of DXA: potential impact on serial measurements and misclassification of osteoporosis. Osteoporos Int. 2001;12:49–54
  9. Schneyer CR, Orbach N. 2001 Frequency of technical errors and inaccurate interpretations of bone density measurements. Phoenix, AZ: ASBMR, 2001.
  10. Gafni RI, Baron J. Overdiagnosis of osteoporosis in children due to misinterpretation of dual x-ray absorptiometry (DEXA). J Pediatr. 2004;144:253–257
  11. Blake GM, Herd RJM, Patel R, Fogelman I. The effect of weight change on total body dual-energy x-ray absorptiometry: results from a clinical trial. Osteoporos Int. 2000;11:832–839
  12. Faulkner KG. Bone matters: are density increases necessary to reduce fracture risk?. J Bone Miner Res. 2000;15:183–186
  13. Cummings SR, Palermo L, Browner W, et al. Monitoring osteoporosis therapy with bone densitometry–misleading changes and regression to the mean. JAMA. 2000;83:1318–1321
  14. Nguyen TV, Pocock NA, Eisman JA. Interpretation of bone mineral density measurement and its change. J Clin. Densitom. 2000;3:107–119
  15. Lenchik L, Kiebzak GM, Blunt BA. Position statement: what is the role of serial bone mineral density measurements in patient management?. J Clin Densitom. 2002;3(Suppl):S29–S38
  16. Bonnick SL. Monitoring changes in bone density. In: Bone Densitometry in Clinical Practice. 2nd ed.. New Jersey: Humana Press; 2004;p. 267–285
  17. Sarkar S, Mitlak BH, Wong M, et al. Relationships between bone mineral density and incident vertebral fracture risk with raloxifene therapy. J Bone Miner Res. 2002;17:1–10

PII: S1094-6950(06)00255-1

doi: 10.1016/j.jocd.2006.08.006

Journal of Clinical Densitometry
Volume 9, Issue 4 , Pages 419-424 , October 2006

Article Tools