Journal of Clinical Densitometry
Volume 9, Issue 3 , Pages 315-322 , July 2006

Simulated Change in Body Fatness Affects Hologic QDR 4500A Whole Body and Central DXA Bone Measures

  • Ellen M. Evans

      Affiliations

    • Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, IL
    • Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL
    • Corresponding Author InformationAddress correspondence to: Ellen M. Evans, 215 Freer Hall, MC-052, 906 S. Goodwin Ave., Department of Kinesiology & Community Health, University of Illinois, Urbana, IL 61801.
    • ,
  • Mina C. Mojtahedi

      Affiliations

    • Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL
    • ,
  • Renee B. Kessinger

      Affiliations

    • Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, IL
    • ,
  • Mark M. Misic

      Affiliations

    • Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, IL

Received 27 January 2006 ,Accepted 21 April 2006.

References 

  1. Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM. Prevalance of overweight and obesity in the United States, 1999–2004. JAMA. 2006;295:1549–1555
  2. Kanis JA. Diagnosis of osteoporosis and assessment of fracture risk. Lancet. 2002;359:1929–1936
  3. Svendsen OL, Hassager C, Christiansen C. Effect of an energy-restrictive diet, with or without exercise, on lean tissue mass, resting metabolic rate, cardiovascular risk factors, and bone in overweight postmenopausal women. Am J Med. 1993;95:131–140
  4. Compston JE, Laskey MA, Croucher PI, Coxon A, Kreitzman S. Effect of diet-induced weight loss on total body bone mass. Clin Sci. 1992;82:429–432
  5. Ryan AS, Nicklas BJ, Dennis KE. Aerobic exercise maintains regional bone mineral density during weight loss in postmenopausal women. J Appl Physiol. 1998;84:1305–1310
  6. Jensen LB, Quaade F, Sorensen OH. Bone loss accompanying voluntary weight loss in obese humans. J Bone Min Res. 1994;9:459–463
  7. Langlois JA, Mussolino MW, Visser M, Looker AC, Harris T, Madans J. Weight loss from maximum body weight among middle-aged and older white women and the risk of hip fracture: the NHANES I epidemiologic follow-up study. Osteoporos Int. 2001;12:763–768
  8. Kamel HK. Male osteoporosis: new trends in diagnosis and therapy. Drugs Aging. 2005;22:741–748
  9. Villareal DT, Apovian CM, Kushner RF, Klein S. Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society. Am J Clin Nutr. 2005;82:923–934
  10. Kohrt WM. Preliminary evidence that DEXA provides an accurate assessment of body composition. J Appl Physiol. 1998;84:372–377
  11. Tothill P, Hannan WJ, Wilkinson S. Comparisons between a pencil beam and two fan beam dual energy X-ray absorptiometers used for measuring total body bone and soft tissue. Br J Rad. 2001;74:166–176
  12. Tothill P, Hannan WJ. Comparisons between Hologic QDR 1000W, QDR4500A, and Lunar Expert dual-energy x-ray absorptiometry scanners used for measuring total body bone and soft tissue. Ann NY Acad Sci. 2000;904:63–71
  13. Tothill P, Hannan WJ, Cowen S, Freeman CP. Anomalies in the measurement of changes in total-body bone mineral by dual-energy X-ray absorptiometry during weight change. J Bone Miner Res. 1997;12:1908–1921
  14. Laskey MA, Murgatroyd PR, Prentice A. Comparison of narrow-angle fan-beam and pencil-beam densitometers. J Clin Densitom. 2004;7:341–348
  15. Anonymous . Measurement of bone density in the lumbar spine: the PA Spine Scan. In:  Blake GM,  Wahner HW,  Fogelman I editor. The evaluation of osteoporosis: dual energy X-ray absorptiometry and ultrasound in clinical practice. London: Martin Dunitz Ltd; 1999;p. 193–233
  16. Espeland MA, Stefanick ML, Kritz-Silverstein D, et al., the Postmenopausal Estrogen Progestin Intervention study investigators  Effect of postmenopausal hormone therapy on body weight and waist and hip girths. J Clin Endocrinol Metab. 1997;82:1549–1556
  17. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;1:307–310
  18. Altman DG, Bland JM. Measurement in medicine: the analysis of method comparison studies. Statistician. 1983;32:307–317
  19. Anonymous . Soft tissue determinants of bone mineral density. In:  Khan K,  McKay H,  Kannus P editor. Physical activity and bone health. Champaign: Human Kinetics; 2001;p. 71–77
  20. Gozansky WS, Van Pelt RE, Jankowski CM, Schwartz RS, Kohrt WM. Protection of bone mass by estrogens and Raloxifene during exercise-induced weight loss. J Clin Endocrinol Metab. 2005;90:52–59
  21. NIH National Heart Lung and Blood Institute . Clinical guidelines on the identification, evaluation and treatment of overweight and obesity in adults: the Evidence Report. Obes Res. 1998;6:51S–209S
  22. Tothill P, Laskey MA, Orphanidou CI, Van Wijk M. Anomalies in dual energy X-ray absorptiometry measurements of total-body bone mineral during weight change using Lunar, Hologic and Norland instruments. Br J Radiol. 1999;72:661–669
  23. Svendsen OL, Hendel HW, Gotfredsen A, Pedersen BH, Anderson T. Are soft tissue composition of bone and non-bone pixels in spinal bone mineral measurements by DXA similar? Impact of weight loss. Clin Physiol Funct Imaging. 2002;22:72–77
  24. Tothill P. Dual-energy X-ray absorptiometry measurements of total-body bone mineral during weight change. J Clin Densitom. 2005;8:31–38
  25. Jensen LB, Vestergaard P, Hermann AP, et al. Hormone replacement therapy dissociates fat mass and bone mass, and tends to reduce weight gain in early postmenopausal women: a randomized controlled 5-year clinical trial of the Danish Osteoporosis Prevention Study. J Bone Miner Res. 2003;18:333–342
  26. Ricci TA, Heymsfield SB, Pierson RNJ, Stahl T, Chowdhury HA, Shapses SA. Moderate energy restriction increases bone resorption in obese postmenopausal women. Am J Clin Nutr. 2001;73:347–352
  27. Jensen LB, Kollerup G, Quaade F, Sorensen OH. Bone mineral changes in obese women during a moderate weight loss with and without calcium supplementation. J Bone Miner Res. 2001;16:141–147
  28. Cordero-MacIntyre ZR, Peters W, Libanati CR, et al. Reproducibility of DXA in obese women. J Clin Densitom. 2002;5:35–44

PII: S1094-6950(06)00191-0

doi: 10.1016/j.jocd.2006.04.117

Journal of Clinical Densitometry
Volume 9, Issue 3 , Pages 315-322 , July 2006

Article Tools

* Image Usage & Resolution