Journal of Clinical Densitometry
Volume 9, Issue 1 , Pages 58-65 , January 2006

Ibandronate: The Evolution of a Once-a-Month Oral Therapy for Postmenopausal Osteoporosis

  • David W. Dempster

      Affiliations

    • Department of Pathology, Columbia University, New York, NY and Regional Bone Center, Helen Hayes Hospital, West Haverstraw, NY
    • Corresponding Author InformationAddress correspondence to David W. Dempster, PhD, Director, Regional Bone Center, Helen Hayes Hospital, Route 9W, West Haverstraw, NY 10993.
  • ,
  • Michael A. Bolognese

      Affiliations

    • Bethesda Health Research, Bethesda, MD

Received 26 July 2005 ,Revised 23 September 2005 ,Accepted 23 September 2005.

  • Image Result

    The basic structure of bisphosphonates. Reprinted with permission from Barrett et al. (44).

    The basic structure of bisphosphonates. Reprinted with permission from Barrett et al. (44).

  • Image Result

    Cumulative effect of oral daily and intermittent ibandronate on new radiographic vertebral fractures during each year of a 3-yr study. Reprinted with permission from Chesnut et al. (43).

    Cumulative effect of oral daily and intermittent ibandronate on new radiographic vertebral fractures during each year of a 3-yr study. Reprinted with permission from Chesnut et al. (43).

  • Image Result

    Mean (standard deviation) percent change from baseline in lumbar spine bone mineral density with daily and monthly oral ibandronate after 1 yr (per protocol population). Reprinted with permission from

    Mean (standard deviation) percent change from baseline in lumbar spine bone mineral density with daily and monthly oral ibandronate after 1 yr (per protocol population). Reprinted with permission from Miller et al. (26).

PII: S1094-6950(06)00018-7

doi: 10.1016/j.jocd.2005.09.004

Journal of Clinical Densitometry
Volume 9, Issue 1 , Pages 58-65 , January 2006